1859. Significance of Bacteremia in Left Ventricular Assist Device Infections due to <i>Pseudomonas aeruginosa</i>
نویسندگان
چکیده
Abstract Background Infection is one of the most common complications Left Ventricular Assist Devices (LVADs). Pseudomonas aeruginosa (PsA) LVAD infections in particular are challenging due to limited antibiotic options and tendency form biofilm making eradication difficult. In this study we examined implications bacteremia patients with PsA infections. Methods This was a retrospective treated at our institution between July 1, 2007 February 2021 who had proven or probable driveline infection (DLI), pump pocket, pump/cannula according International Society for Heart & Lung Transplantation criteria. Results Of 717 an LVAD, 51 VAD-specific PsA.16/51 (31%) bloodstream associated VAD infection, median 400 days from initial diagnosis. Only 29% those DLI were bacteremic, vs. 66% pocket 50% mediastinitis (Fig 1). Patients developed 3 episodes (range, 1-5). All but 1 patient received surgery. 16 bacteremia, 11 (69%) died vs 9/35 (26%) not bacteremic 2). 10/11 driveline. 21/41 (51%) identified, already on antibiotics duration 49 (7-198) prior onset bacteremia. Conclusion A significant number develop especially involvement central components. The presence should prompt evaluation ascending infection. Most died, even when appeared driveline, it possible that endoluminal present these cases. substantial proportion time which suggests suppressive alone may be effective controlling Disclosures Authors: No reported disclosures.
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2022
ISSN: ['2328-8957']
DOI: https://doi.org/10.1093/ofid/ofac492.1488